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Population pharmacokinetic analysis of metformin administered as fixed-dose combination in Korean healthy adults

Metformin, an oral antihyperglycemic agent, is widely used as the first-line pharmacotherapy for type 2 diabetes mellitus (T2DM). It has been in use for several decades as numerous different formulations. However, despite its use, population pharmacokinetic (PK) modeling of metformin is not well dev...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Transl Clin Pharmacol
Hauptverfasser: Choi, Suein, Jeon, Sangil, Han, Seunghoon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society for Clinical Pharmacology and Therapeutics 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989222/
https://ncbi.nlm.nih.gov/pubmed/32055544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2018.26.1.25
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