In Silico Docking of Alkylphosphocholine Analogs to Human Serum Albumin Predict Partitioning and Pharmacokinetics

Alkylphosphocholine (APC) analogs are a novel class of broad-spectrum tumor-targeting agents that can be used for both diagnosis and treatment of cancer. The potential for clinical translation for APC analogs will strongly depend on their pharmacokinetic (PK) profiles. The aim of this work was to un...

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Vydáno v:Mol Pharm
Hlavní autoři: Zhang, Ray R., Grudzinksi, Joseph J., Mehta, Tej I., Burnette, Ronald R., Hernandez, Reinier, Clark, Paul A., Lubin, Jonathan A., Pinchuk, Anatoly N., Jeffrey, Justin, Longino, Marc, Kuo, John S., Weichert, Jamey P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989153/
https://ncbi.nlm.nih.gov/pubmed/31082240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b01301
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