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A Novel Resistance Pathway for Calcineurin Inhibitors in the Human-Pathogenic Mucorales Mucor circinelloides

Mucormycosis is an emerging lethal fungal infection in immunocompromised patients. Mucor circinelloides is a causal agent of mucormycosis and serves as a model system to understand genetics in Mucorales. Calcineurin is a conserved virulence factor in many pathogenic fungi, and calcineurin inhibition...

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Détails bibliographiques
Publié dans:mBio
Auteurs principaux: Vellanki, Sandeep, Billmyre, R. Blake, Lorenzen, Alejandra, Campbell, Micaela, Turner, Broderick, Huh, Eun Young, Heitman, Joseph, Lee, Soo Chan
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989107/
https://ncbi.nlm.nih.gov/pubmed/31992620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02949-19
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