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Broad antifungal resistance mediated by RNAi-dependent epimutation in the basal human fungal pathogen Mucor circinelloides

Mucormycosis—an emergent, deadly fungal infection—is difficult to treat, in part because the causative species demonstrate broad clinical antifungal resistance. However, the mechanisms underlying drug resistance in these infections remain poorly understood. Our previous work demonstrated that one ma...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Chang, Zanetta, Billmyre, R. Blake, Lee, Soo Chan, Heitman, Joseph
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386414/
https://ncbi.nlm.nih.gov/pubmed/30742617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007957
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