A CRISPR-Assisted Nonhomologous End-Joining Strategy for Efficient Genome Editing in Mycobacterium tuberculosis

New tools for genetic manipulation of Mycobacterium tuberculosis are needed for the development of new drug regimens and vaccines aimed at curing tuberculosis infections. Clustered regularly interspaced short palindromic repeat (CRISPR)–CRISPR-associated protein (Cas) systems generate a highly speci...

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Publicat a:mBio
Autors principals: Yan, Mei-Yi, Li, Si-Shang, Ding, Xin-Yuan, Guo, Xiao-Peng, Jin, Qi, Sun, Yi-Cheng
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989103/
https://ncbi.nlm.nih.gov/pubmed/31992616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02364-19
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