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Efficient Gene Replacements in Toxoplasma gondii Strains Deficient for Nonhomologous End Joining
A high frequency of nonhomologous recombination has hampered gene targeting approaches in the model apicomplexan parasite Toxoplasma gondii. To address whether the nonhomologous end-joining (NHEJ) DNA repair pathway could be disrupted in this obligate intracellular parasite, putative KU proteins wer...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669201/ https://ncbi.nlm.nih.gov/pubmed/19218423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00357-08 |
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