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Efficient Gene Replacements in Toxoplasma gondii Strains Deficient for Nonhomologous End Joining

A high frequency of nonhomologous recombination has hampered gene targeting approaches in the model apicomplexan parasite Toxoplasma gondii. To address whether the nonhomologous end-joining (NHEJ) DNA repair pathway could be disrupted in this obligate intracellular parasite, putative KU proteins wer...

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Bibliografiset tiedot
Päätekijät: Fox, Barbara A., Ristuccia, Jessica G., Gigley, Jason P., Bzik, David J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2009
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669201/
https://ncbi.nlm.nih.gov/pubmed/19218423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00357-08
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