Macrophage FABP4 is required for neutrophil recruitment and bacterial clearance in Pseudomonas aeruginosa pneumonia

Fatty acid binding protein 4 (FABP4), an intracellular lipid chaperone and adipokine, is expressed by lung macrophages, but the function of macrophage–FABP4 remains elusive. We investigated the role of FABP4 in host defense in a murine model of Pseudomonas aeruginosa pneumonia. Compared with wild-ty...

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Bibliografiske detaljer
Udgivet i:FASEB J
Main Authors: Liang, Xiaoliang, Gupta, Kushagra, Quintero, Joselyn Rojas, Cernadas, Manuela, Kobzik, Lester, Christou, Helen, Pier, Gerald B., Owen, Caroline A., Çataltepe, Sule
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988858/
https://ncbi.nlm.nih.gov/pubmed/30462529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802002R
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