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Role of Neutrophils, MyD88-Mediated Neutrophil Recruitment, and Complement in Antibody-Mediated Defense against Pseudomonas aeruginosa Keratitis

PURPOSE. Ulcerative keratitis due to Pseudomonas aeruginosa is a sight-threatening disease leading to loss of vision due to corneal inflammation. A human IgG1 monoclonal antibody (MAb F429) to the alginate capsule significantly reduces pathology and bacterial burdens in the cornea when applied topic...

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Détails bibliographiques
Auteurs principaux: Zaidi, Tanweer S., Zaidi, Tauqeer, Pier, Gerald B.
Format: Artigo
Langue:Inglês
Publié: Association for Research in Vision and Ophthalmology, Inc. 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868398/
https://ncbi.nlm.nih.gov/pubmed/19892865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4139
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