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Rock-paper-scissors: Engineered population dynamics increase genetic stability

Advances in synthetic biology have led to an arsenal of proof-of-principle bacterial circuits that can be leveraged for applications ranging from therapeutics to bioproduction. A unifying challenge for most applications is the presence of selective pressures that lead to high mutation rates for engi...

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Vydáno v:Science
Hlavní autoři: Liao, Michael J., Din, M. Omar, Tsimring, Lev, Hasty, Jeff
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988775/
https://ncbi.nlm.nih.gov/pubmed/31488693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaw0542
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