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Suppression of Beneficial Mutations in Dynamic Microbial Populations

Quantitative predictions for the spread of mutations in bacterial populations are essential to interpret evolution experiments and to improve the stability of synthetic gene circuits. We derive analytical expressions for the suppression factor for beneficial mutations in populations that undergo per...

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Bibliographic Details
Published in:Phys Rev Lett
Main Authors: Bittihn, Philip, Hasty, Jeff, Tsimring, Lev S.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552243/
https://ncbi.nlm.nih.gov/pubmed/28128631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevLett.118.028102
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