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Suppression of Beneficial Mutations in Dynamic Microbial Populations

Quantitative predictions for the spread of mutations in bacterial populations are essential to interpret evolution experiments and to improve the stability of synthetic gene circuits. We derive analytical expressions for the suppression factor for beneficial mutations in populations that undergo per...

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Publicat a:Phys Rev Lett
Autors principals: Bittihn, Philip, Hasty, Jeff, Tsimring, Lev S.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552243/
https://ncbi.nlm.nih.gov/pubmed/28128631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevLett.118.028102
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