N-acetylcysteine inhibits thrombosis in a murine model of myeloproliferative neoplasm

Thrombosis is a major cause of mortality in patients with myeloproliferative neoplasms (MPNs), though there is currently little to offer patients with MPN beyond aspirin and cytoreductive therapies such as hydroxyurea for primary prevention. Thrombogenesis in MPN involves multiple cellular mechanism...

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Bibliographic Details
Published in:Blood Adv
Main Authors: Craver, Brianna M., Ramanathan, Gajalakshmi, Hoang, Summer, Chang, Xinyue, Mendez Luque, Laura F., Brooks, Stefan, Lai, Hew Yeng, Fleischman, Angela G.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2020
Subjects:
Myeloid Neoplasia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988398/
https://ncbi.nlm.nih.gov/pubmed/31978215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000967
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