The protective effects of PI3K/Akt pathway on human nucleus pulposus mesenchymal stem cells against hypoxia and nutrition deficiency

BACKGROUND: To study the effects of hypoxia and nutrition deficiency mimicking degenerated intervertebral disc on the biological behavior of human nucleus-derived pulposus mesenchymal stem cells (hNP-MSCs) and the role of PI3K/Akt pathway in the process in vitro. METHODS: hP-MSCs were isolated from...

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Pubblicato in:J Orthop Surg Res
Autori principali: Tian, DaSheng, Liu, Jianjun, Chen, Lei, Zhu, Bin, Jing, Juehua
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988348/
https://ncbi.nlm.nih.gov/pubmed/31992313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-020-1551-9
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