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Engineered disulfide crosslinking to measure conformational changes in the 26S proteasome
The 26S proteasome is a multisubunit ATP-dependent peptidase complex mediating most regulated protein degradation in eukaryotes. The proteasome undergoes several coordinated conformational changes during catalysis that activate it for substrate processing and functionally couple distinct enzymatic a...
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| Publicado no: | Methods Enzymol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6987956/ https://ncbi.nlm.nih.gov/pubmed/30910019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.11.006 |
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