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Understanding the Complexity of the Tumor Microenvironment in K-ras Mutant Lung Cancer: Finding an Alternative Path to Prevention and Treatment

Kirsten rat sarcoma viral oncogene (K-ras) is a well-documented, frequently mutated gene in lung cancer. Since K-ras regulates numerous signaling pathways related to cell survival and proliferation, mutations in this gene are powerful drivers of tumorigenesis and confer prodigious survival advantage...

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發表在:Front Oncol
Main Authors: Deng, Shanshan, Clowers, Michael J., Velasco, Walter V., Ramos-Castaneda, Marco, Moghaddam, Seyed Javad
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987304/
https://ncbi.nlm.nih.gov/pubmed/32039025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01556
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