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Calponin-3 deficiency augments contractile activity, plasticity, fibrogenic response and Yap/Taz transcriptional activation in lens epithelial cells and explants

The transparent ocular lens plays a crucial role in vision by focusing light on to the retina with loss of lens transparency leading to impairment of vision. While maintenance of epithelial phenotype is recognized to be essential for lens development and function, knowledge of the identity of differ...

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Publicado no:Sci Rep
Main Authors: Maddala, Rupalatha, Mongan, Maureen, Xia, Ying, Rao, Ponugoti Vasantha
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987178/
https://ncbi.nlm.nih.gov/pubmed/31992794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58189-y
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