Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma

L-type amino acid transporter 1 (LAT1) plays a role in transporting essential amino acids including leucine, which regulates the mTOR signaling pathway. Here, we studied the expression profile and functional role of LAT1 in bladder cancer. Furthermore, the pharmacological activity of JPH203, a speci...

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發表在:Sci Rep
Main Authors: Maimaiti, Maihulan, Sakamoto, Shinichi, Yamada, Yasutaka, Sugiura, Masahiro, Rii, Junryo, Takeuchi, Nobuyoshi, Imamura, Yusuke, Furihata, Tomomi, Ando, Keisuke, Higuchi, Kosuke, Xu, Minhui, Sazuka, Tomokazu, Nakamura, Kazuyoshi, Kaneda, Atsushi, Kanai, Yoshikatsu, Kyprianou, Natasha, Ikehara, Yuzuru, Anzai, Naohiko, Ichikawa, Tomohiko
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987139/
https://ncbi.nlm.nih.gov/pubmed/31992742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58136-x
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