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Cucurbitacin B and I inhibits colon cancer growth by targeting the Notch signaling pathway
Cancer stem cells (CSCs) have the ability to self-renew and induce drug resistance and recurrence in colorectal cancer (CRC). As current chemotherapy doesn’t eliminate CSCs completely, there is a need to identify novel agents to target them. We investigated the effects of cucurbitacin B (C-B) or I (...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6987129/ https://ncbi.nlm.nih.gov/pubmed/31992775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57940-9 |
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