Honokiol Inhibits Melanoma Stem Cells by Targeting Notch Signaling

Melanoma is an aggressive disease with limited therapeutic options. Here, we determined the effects of honokiol (HNK), a biphenolic natural compound on melanoma cells and stemness. HNK significantly inhibited melanoma cell proliferation, viability, clonogenicity and induced autophagy. In addition, H...

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Bibliographic Details
Published in:Mol Carcinog
Main Authors: Kaushik, Gaurav, Venugopal, Anand, Ramamoorthy, Prabhu, Standing, David, Subramaniam, Dharmalingam, Umar, Shahid, Jensen, Roy A., Anant, Shrikant, Mammen, Joshua M.V.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776032/
https://ncbi.nlm.nih.gov/pubmed/25491779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22242
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