Tracing the origin of adult intestinal stem cells

Adult Intestinal Stem Cells (ISCs) are located at the bottom of crypts of Lieberkühn, where they express markers such as Lgr5(1,2), and fuel the constant replenishment of the intestinal epithelium(1). Although fetal Lgr5 expressing cells can give rise to adult ISCs(3,4), it remains unclear whether t...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Guiu, Jordi, Hannezo, Edouard, Yui, Shiro, Demharter, Samuel, Ulyanchenko, Svetlana, Maimets, Martti, Jørgensen, Anne, Perlman, Signe, Lundvall, Lene, Mamsen, Linn Salto, Larsen, Agnete, Olesen, Rasmus H., Andersen, Claus Yding, Thuesen, Lea Langhoff, Hare, Kristine Juul, Pers, Tune H., Khodosevich, Konstantin, Simons, Benjamin D., Jensen, Kim B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986928/
https://ncbi.nlm.nih.gov/pubmed/31092921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1212-5
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