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Targeted delivery of TNF potentiates the antibody-dependent cell-mediated cytotoxicity of an anti-melanoma immunoglobulin

IgG therapeutics directed against solid tumor antigens can be effective in preventing disseminated cancer spread in mouse models, but are typically ineffective in eradicating established solid tumor masses. Here, we have studied the anti-tumor activity of the recombinant murine IgG2a antibody TA99,...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Murer, Patrizia, Kiefer, Jonathan D, Plüss, Louis, Matasci, Mattia, Bluemich, Sandra, Neri, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986903/
https://ncbi.nlm.nih.gov/pubmed/30543899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2018.11.028
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