Decreased expression of a phagocytic receptor Siglec-1 on alveolar macrophages in chronic obstructive pulmonary disease

BACKGROUND: Alveolar macrophages are professional phagocytes that remove microbial pathogens inhaled into the lung. The phagocytic ability is compromised in chronic obstructive pulmonary disease (COPD). However, the molecular mechanisms underlying this defect in phagocytosis are not clearly defined....

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Tanno, Atsushi, Fujino, Naoya, Yamada, Mitsuhiro, Sugiura, Hisatoshi, Hirano, Taizou, Tanaka, Rie, Sano, Hirohito, Suzuki, Satoshi, Okada, Yoshinori, Ichinose, Masakazu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986024/
https://ncbi.nlm.nih.gov/pubmed/31992280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-020-1297-2
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