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PGC-1α regulates airway epithelial barrier dysfunction induced by house dust mite

BACKGROUND: The airway epithelial barrier function is disrupted in the airways of asthmatic patients. Abnormal mitochondrial biogenesis is reportedly involved in the pathogenesis of asthma. However, the role of mitochondrial biogenesis in the airway barrier dysfunction has not been elucidated yet. T...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Saito, Tsutomu, Ichikawa, Tomohiro, Numakura, Tadahisa, Yamada, Mitsuhiro, Koarai, Akira, Fujino, Naoya, Murakami, Koji, Yamanaka, Shun, Sasaki, Yusaku, Kyogoku, Yorihiko, Itakura, Koji, Sano, Hirohito, Takita, Katsuya, Tanaka, Rie, Tamada, Tsutomu, Ichinose, Masakazu, Sugiura, Hisatoshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7893966/
https://ncbi.nlm.nih.gov/pubmed/33607992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-021-01663-6
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