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Botox injection into the lower esophageal sphincter induces hiatal paralysis and gastroesophageal reflux

Background: Endoscopic intrasphincteric injection of Botox (ISIB) is used routinely for the treatment of achalasia esophagus and other spastic motor disorders. Studies show that the ISIB reduces the smooth muscle lower esophageal sphincter (LES) pressure. The esophageal hiatus, formed by the right c...

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Pubblicato in:Am J Physiol Gastrointest Liver Physiol
Autori principali: Kumar, Dushyant, Zifan, Ali, Mittal, Ravinder K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985847/
https://ncbi.nlm.nih.gov/pubmed/31589467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00238.2019
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