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Botox injection into the lower esophageal sphincter induces hiatal paralysis and gastroesophageal reflux

Background: Endoscopic intrasphincteric injection of Botox (ISIB) is used routinely for the treatment of achalasia esophagus and other spastic motor disorders. Studies show that the ISIB reduces the smooth muscle lower esophageal sphincter (LES) pressure. The esophageal hiatus, formed by the right c...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Kumar, Dushyant, Zifan, Ali, Mittal, Ravinder K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985847/
https://ncbi.nlm.nih.gov/pubmed/31589467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00238.2019
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