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New Triazole NT-a9 Has Potent Antifungal Efficacy against Cryptococcus neoformans In Vitro and In Vivo

In the past decades, the incidence of cryptococcosis has increased dramatically, which poses a new threat to human health. However, only a few drugs are available for the treatment of cryptococcosis. Here, we described a leading compound, NT-a9, an analogue of isavuconazole, that showed strong antif...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Lu, Ren-Yi, Ni, Ting-Jun-Hong, Wu, Jing, Yan, Lan, Lv, Quan-Zhen, Li, Li-Ping, Zhang, Da-Zhi, Jiang, Yuan-Ying
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985734/
https://ncbi.nlm.nih.gov/pubmed/31791946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01628-19
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