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Effects of Antifungal Interventions on the Outcome of Experimental Infections with Phenotypic Switch Variants of Cryptococcus neoformans

In cryptococcal infection, phenotypic switching from a smooth to a mucoid variant can occur in vivo, producing variants with enhanced virulence that are subsequently selected and affect the outcome of infection. Here, we demonstrate that antifungal treatment of the chronically infected host can prom...

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Autors principals: Fries, Bettina C., Cook, Emily, Wang, Xiabo, Casadevall, Arturo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC538904/
https://ncbi.nlm.nih.gov/pubmed/15616315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.350-357.2005
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