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Isolation and Characterization of Senescent Cryptococcus neoformans and Implications for Phenotypic Switching and Pathogenesis in Chronic Cryptococcosis

Although several virulence factors and associated genes have been identified, the mechanisms that allow Cryptococcus neoformans to adapt during chronic infection and to persist in immunocompromised hosts remain poorly understood. Characterization of senescent cells of C. neoformans demonstrated that...

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Detalhes bibliográficos
Main Authors: Jain, Neena, Cook, Emily, Xess, Immaculata, Hasan, Fahmi, Fries, Dietrich, Fries, Bettina C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698302/
https://ncbi.nlm.nih.gov/pubmed/19411622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00017-09
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