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TIM‐4 interference in Kupffer cells against CCL4‐induced liver fibrosis by mediating Akt1/Mitophagy signalling pathway

OBJECTIVES: T‐cell immunoglobulin domain and mucin domain‐4 (TIM‐4) is selectively expressed on antigen‐presenting cells (APCs) and modulates various immune responses. However, the role of TIM‐4 expressed by Kupffer cells (KCs) in liver fibrosis remains unclear. The present study aimed to explore wh...

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Détails bibliographiques
Publié dans:Cell Prolif
Auteurs principaux: Wu, Hao, Chen, Guoyong, Wang, Jingyuan, Deng, Minghua, Yuan, Fangchao, Gong, Jianping
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985653/
https://ncbi.nlm.nih.gov/pubmed/31755616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12731
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