Blockade of CCN4 attenuates CCl(4)-induced liver fibrosis

INTRODUCTION: CCN4, also termed WNT-inducible signaling pathway protein-1 (WISP-1), has important roles in inflammation and tissue injury. This study aimed to investigate the effect of CCN4 inhibition using monoclonal anti-CCN4 antibody (CCN4mAb) on the liver injury and fibrosis in a mouse model of...

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Dettagli Bibliografici
Pubblicato in:Arch Med Sci
Autori principali: Li, Xiaofei, Chen, Yongxin, Ye, Weiwei, Tao, Xingfei, Zhu, Jinhong, Wu, Shuang, Lou, Lianqing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Termedia Publishing House 2015
Soggetti:
Experimental Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495160/
https://ncbi.nlm.nih.gov/pubmed/26170860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2015.52371
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