טוען...
Cell-Autonomous and Non-cell-Autonomous Pathogenic Mechanisms in Huntington’s Disease: Insights from In Vitro and In Vivo Models
Huntington’s disease (HD) is an autosomal dominant disorder caused by an expansion in the trinucleotide CAG repeat in exon-1 in the huntingtin gene, located on chromosome 4. When the number of trinucleotide CAG exceeds 40 repeats, disease invariably is manifested, characterized by motor, cognitive,...
שמור ב:
| הוצא לאור ב: | Neurotherapeutics |
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| Main Authors: | , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Springer International Publishing
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6985401/ https://ncbi.nlm.nih.gov/pubmed/31529216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-019-00782-9 |
| תגים: |
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