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Stabilized Reconstruction of Signaling Networks from Single-Cell Cue-Response Data

Inferring cell-signaling networks from high-throughput data is a challenging problem in systems biology. Recent advances in cytometric technology enable us to measure the abundance of a large number of proteins at the single-cell level across time. Traditional network reconstruction approaches usual...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kumar, Sunil, Lun, Xiao-Kang, Bodenmiller, Bernd, Rodríguez Martínez, María, Koeppl, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985232/
https://ncbi.nlm.nih.gov/pubmed/31988302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56444-5
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