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The concentration of tumor necrosis factor-α determines its protective or damaging effect on liver injury by regulating Yap activity

Previous studies have shown that tumor necrosis factor (TNF)-α is a mediator of hepatotoxicity in liver injury. Moreover, TNF-α has also been reported to have a protective effect in liver regeneration, yet the function of TNF-α during liver injury remains controversial. Here, we report that the conc...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhao, Shanmin, Jiang, Jinghua, Jing, Yingying, Liu, Wenting, Yang, Xue, Hou, Xiaojuan, Gao, Lu, Wei, Lixin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985193/
https://ncbi.nlm.nih.gov/pubmed/31988281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2264-z
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