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Simultaneous Knockdown of Sprouty2 and PTEN Promotes Axon Elongation of Adult Sensory Neurons

Sprouty2 (Spry2) and phosphatase and tensin homolog deleted on chromosome 10 (PTEN) are both well-established regulators of receptor tyrosine kinase (RTK) signaling, and knockdown of Spry2 or PTEN enhances axon regeneration of dorsal root ganglia (DRG) neurons. The major role of Spry2 is the inhibit...

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Detalles Bibliográficos
Publicado en:Front Cell Neurosci
Main Authors: Jamsuwan, Sataporn, Klimaschewski, Lars, Hausott, Barbara
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985068/
https://ncbi.nlm.nih.gov/pubmed/32038175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00583
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