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Forged by DXZ4, FIRRE, and ICCE: How Tandem Repeats Shape the Active and Inactive X Chromosome

Recent efforts in mapping spatial genome organization have revealed three evocative and conserved structural features of the inactive X in female mammals. First, the chromosomal conformation of the inactive X reveals a loss of topologically associated domains (TADs) present on the active X. Second,...

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Publicat a:Front Cell Dev Biol
Autors principals: Bansal, Prakhar, Kondaveeti, Yuvabharath, Pinter, Stefan F.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985041/
https://ncbi.nlm.nih.gov/pubmed/32076600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00328
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