Proteasomal adaptations underlying carfilzomib-resistance in human bone marrow plasma cells

Donor-specific antibodies (DSAs) have a deleterious effect on allografts and remain a major immunologic barrier in transplantation. Current therapies to eliminate DSAs are ineffective in highly human leukocyte antigen (HLA)-sensitized patients. Proteasome inhibitors have been employed as a strategy...

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Gepubliceerd in:Am J Transplant
Hoofdauteurs: Woodle, E.S., Tremblay, S., Brailey, P., Girnita, A., Alloway, R.R., Aronow, B., Dasgupta, N., Ebstein, F., Kloetzel, P.M., Lee, M.J., Kim, K.B., Singh, H., Driscoll, J.J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984988/
https://ncbi.nlm.nih.gov/pubmed/31595669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15634
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