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Clonal analysis of Notch1-expressing cells reveals the existence of unipotent stem cells that retain long-term plasticity in the embryonic mammary gland

Recent lineage tracing studies revealed that mammary gland homeostasis relies on unipotent stem cells. However, whether and when lineage restriction occurs during embryonic mammary development and which signals orchestrate cell fate specification remain unknown. Using a combination of in vivo clonal...

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Publicado en:Nat Cell Biol
Autores principales: Lilja, Anna M., Rodilla, Veronica, Huyghe, Mathilde, Hannezo, Edouard, Landragin, Camille, Renaud, Olivier, Leroy, Olivier, Rulands, Steffen, Simons, Benjamin D., Fre, Silvia
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984964/
https://ncbi.nlm.nih.gov/pubmed/29784917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0108-1
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