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Clonal analysis of Notch1-expressing cells reveals the existence of unipotent stem cells that retain long-term plasticity in the embryonic mammary gland

Recent lineage tracing studies revealed that mammary gland homeostasis relies on unipotent stem cells. However, whether and when lineage restriction occurs during embryonic mammary development and which signals orchestrate cell fate specification remain unknown. Using a combination of in vivo clonal...

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Pubblicato in:Nat Cell Biol
Autori principali: Lilja, Anna M., Rodilla, Veronica, Huyghe, Mathilde, Hannezo, Edouard, Landragin, Camille, Renaud, Olivier, Leroy, Olivier, Rulands, Steffen, Simons, Benjamin D., Fre, Silvia
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984964/
https://ncbi.nlm.nih.gov/pubmed/29784917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0108-1
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