Fluorescent Crimean-Congo hemorrhagic fever virus illuminates tissue tropism patterns and identifies early mononuclear phagocytic cell targets in Ifnar(-/-) mice

Crimean-Congo hemorrhagic fever virus (CCHFV, order Bunyavirales, family Nairoviridae, genus Orthonairovirus) is the tick-borne etiological agent of Crimean-Congo hemorrhagic fever (CCHF) in humans. Animals are generally susceptible to CCHFV infection but refractory to disease. Small animal models a...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Welch, Stephen R., Ritter, Jana M., McElroy, Anita K., Harmon, Jessica R., Coleman-McCray, JoAnn D., Scholte, Florine E. M., Kobinger, Gary P., Bergeron, Éric, Zaki, Sherif R., Nichol, Stuart T., Spengler, Jessica R., Spiropoulou, Christina F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984736/
https://ncbi.nlm.nih.gov/pubmed/31790513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008183
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