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Neuronal autophagy declines substantially with age and is rescued by overexpression of WIPI2
Macroautophagy/autophagy is implicated in age-dependent neurodegenerative diseases, including amyotrophic lateral sclerosis and Parkinson, Huntington and Alzheimer diseases, suggesting that an age-related decline in neuronal autophagy may contribute to the onset of neurodegeneration. We identified a...
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| Published in: | Autophagy |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6984449/ https://ncbi.nlm.nih.gov/pubmed/31794336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1695401 |
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