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The Non-amyloidal Component Region of α-Synuclein Is Important for α-Synuclein Transport Within Axons

Proper transport of the Parkinson’s disease (PD) protein, α-synuclein (α-syn), is thought to be crucial for its localization and function at the synapse. Previous work has shown that defects in long distance transport within narrow caliber axons occur early in PD, but how such defects contribute to...

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Pubblicato in:Front Cell Neurosci
Autori principali: Anderson, Eric N., Hirpa, Delnessaw, Zheng, Kan Hong, Banerjee, Rupkatha, Gunawardena, Shermali
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984405/
https://ncbi.nlm.nih.gov/pubmed/32038170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00540
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