Excess active P13K rescues Huntingtin-mediated neuronal cell death but has no effect on axonal transport defects.

High levels of oxidative stress is detected in neurons affected by many neurodegenerative diseases, including Huntington’s disease (HD). Many of these diseases also show neuronal cell death and axonal transport defects. While nuclear inclusions/accumulations likely cause cell death, we previously sh...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Apoptosis
Hlavní autoři: Hansen, Timothy, Thant, Claire, White, Joseph A., Banerjee, Rupkatha, Thuamsang, Bhasirie, Gunawardena, Shermali
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486460/
https://ncbi.nlm.nih.gov/pubmed/30725352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-019-01520-4
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky