Restoration of miR-193a-5p and miR-146 a-5p Expression Induces G1 Arrest in Colorectal Cancer through Targeting of MDM2/p53

Purpose: Colorectal cancer (CRC) remains a universal and lethal cancer owing to metastatic and relapsing disease. Currently, the role of microRNAs has been checked in tumorigeneses. Numerous studies have revealed that between the tumor suppressor miRNAs, the reduced expression of miR-146a-5p and -19...

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Veröffentlicht in:Adv Pharm Bull
Hauptverfasser: Noorolyai, Saeed, Baghbani, Elham, Aghebati Maleki, Leili, Baghbanzadeh Kojabad, Amir, Shanehbansdi, Dariush, Khaze Shahgoli, Vahid, Mokhtarzadeh, Ahad, Baradaran, Behzad
Format: Artigo
Sprache:Inglês
Veröffentlicht: Tabriz University of Medical Sciences 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983996/
https://ncbi.nlm.nih.gov/pubmed/32002372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2020.017
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