Restoration of miR-193a-5p and miR-146 a-5p Expression Induces G1 Arrest in Colorectal Cancer through Targeting of MDM2/p53

Purpose: Colorectal cancer (CRC) remains a universal and lethal cancer owing to metastatic and relapsing disease. Currently, the role of microRNAs has been checked in tumorigeneses. Numerous studies have revealed that between the tumor suppressor miRNAs, the reduced expression of miR-146a-5p and -19...

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Vydáno v:Adv Pharm Bull
Hlavní autoři: Noorolyai, Saeed, Baghbani, Elham, Aghebati Maleki, Leili, Baghbanzadeh Kojabad, Amir, Shanehbansdi, Dariush, Khaze Shahgoli, Vahid, Mokhtarzadeh, Ahad, Baradaran, Behzad
Médium: Artigo
Jazyk:Inglês
Vydáno: Tabriz University of Medical Sciences 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983996/
https://ncbi.nlm.nih.gov/pubmed/32002372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2020.017
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