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Expression and purification of recombinant G protein-coupled receptors: A review

Given their extensive role in cell signalling, GPCRs are significant drug targets; despite this, many of these receptors have limited or no available prophylaxis. Novel drug design and discovery significantly rely on structure determination, of which GPCRs are typically elusive. Progress has been ma...

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Detalhes bibliográficos
Publicado no:Protein Expr Purif
Main Authors: Wiseman, Daniel N., Otchere, Abigail, Patel, Jaimin H., Uddin, Romez, Pollock, Naomi L., Routledge, Sarah J., Rothnie, Alice J., Slack, Cathy, Poyner, David R., Bill, Roslyn M., Goddard, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983937/
https://ncbi.nlm.nih.gov/pubmed/31678667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2019.105524
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