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Src Kinase Is Biphosphorylated at Y416/Y527 and Activates the CUB-Domain Containing Protein 1/Protein Kinase C δ Pathway in a Subset of Triple-Negative Breast Cancers
Targeted therapeutics are needed for triple-negative breast cancer (TNBC). In this study, we investigated the activation of Src family of cytoplasmic tyrosine kinases (SFKs) and two SFK substrates—CUB-domain containing protein 1 (CDCP1) and protein kinase C δ (PKCδ)—in 56 formalin-fixed, paraffin-em...
Gorde:
| Argitaratua izan da: | Am J Pathol |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Investigative Pathology
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6983918/ https://ncbi.nlm.nih.gov/pubmed/31843498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.10.017 |
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