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The balancing act of R-loop biology: The good, the bad, and the ugly

An R-loop is a three-stranded nucleic acid structure that consists of a DNA:RNA hybrid and a displaced strand of DNA. R-loops occur frequently in genomes and have significant physiological importance. They play vital roles in regulating gene expression, DNA replication, and DNA and histone modificat...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hegazy, Youssef A., Fernando, Chrishan M., Tran, Elizabeth J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983857/
https://ncbi.nlm.nih.gov/pubmed/31843970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.011353
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