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Hydroxyurea—The Good, the Bad and the Ugly

Hydroxyurea (HU) is mostly referred to as an inhibitor of ribonucleotide reductase (RNR) and as the agent that is commonly used to arrest cells in the S-phase of the cycle by inducing replication stress. It is a well-known and widely used drug, one which has proved to be effective in treating chroni...

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Pubblicato in:Genes (Basel)
Autori principali: Musiałek, Marcelina W., Rybaczek, Dorota
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304116/
https://ncbi.nlm.nih.gov/pubmed/34356112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12071096
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