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Disruption of hepatic small heterodimer partner induces dissociation of steatosis and inflammation in experimental nonalcoholic steatohepatitis

Nonalcoholic steatohepatitis (NASH) is a leading cause of chronic liver disease worldwide and is characterized by steatosis, inflammation, and fibrosis. The molecular mechanisms underlying NASH development remain obscure. The nuclear receptor small heterodimer partner (Shp) plays a complex role in l...

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書目詳細資料
發表在:J Biol Chem
Main Authors: Magee, Nancy, Zou, An, Ghosh, Priyanka, Ahamed, Forkan, Delker, Don, Zhang, Yuxia
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983844/
https://ncbi.nlm.nih.gov/pubmed/31831621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010233
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